產(chǎn)品屬性:
名稱(chēng) | CRF (human, rat) |
規(guī)格 | 200μg |
貨號(hào) | EY-01Y11963 |
Cas No.: 86784-80-7
分子量: 4757.45
溶解度: Soluble to 1.10 mg/ml in sterile water
儲(chǔ)存條件: Desiccate at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
Corticotropin-releasing factor human (Human CRF; Human corticotropin-releasing factor) stimulates the synthesis and secretion of adrenocorticotropin in the anterior pituitary.CRF increases excitability of type II dlBNST neurons through activation of the AC-cAMP-PKA pathway, thereby causing pain-induced aversive responses[1].The findings are consistent with a mechanism whereby the excess CRF that characterizes stress-related diseases initiates distinct cellular processes in male and female brains, as a result of sex-biased CRF1 signaling[2]. CRF injection on food intake (FI), CRF suppresses FI in 3-month male and female animals[3].
特別提醒公司產(chǎn)品僅供科研使用